Avis d'expert | Mode of Neonatal Delivery Influences the Nutrient Composition of Human Milk
Juillet 2024 | The effect of the mode of neonatal delivery (cesarean or vaginal) on the nutrient composition of human milk (HM) has rarely been studied. Given the increasing prevalence of cesarean section (C-section) globally, understanding the impact of C-section vs. vaginal delivery on the nutrient composition of HM is fundamental when HM is the preferred source of infant food during the first 4 postnatal months.
Samuel TM, Thielecke F, Lavalle L, Chen C, Fogel P et al. Front. Nutr. 9:8344394, 2022.
This study aimed to evaluate the association between mode of delivery and nutrient composition of HM in the first 4 months of life.
Milk samples were obtained from 317 healthy lactating mothers as part of an exploratory analyses within a multicenter European longitudinal cohort (ATLAS cohort) to study the HM composition, and its potential association with the mode of delivery. We employed traditional mixed models to study individual nutrient associations adjusted for mother’s country, infant birth weight, parity, and gestational age, and complemented it, for the first time, with a multidimensional data analyses approach (non-negative tensor factorization, NTF) to examine holistically how patterns of multiple nutrients and changes over time are associated with the delivery mode.
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